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Division of Infectious Diseases


?Research within the Division focuses on several key areas, including:

? People with HIV and TB 
? Pharmacokinetics and safety of tuberculosis drugs during pregnancy and postpartum
? Viral hepatitis – specifically Hepatitis B and HBV/HIV co-infection 
? HIV associated Kaposi’s sarcoma
? Non-TB mycobacterial infections (NTM)
? Infections in the intensive care unit including HIV, TB and hospital acquired infections
? Local outbreaks of infectious diseases including COVID-19, influenza, non-toxogenic C. diphtheria and rabies.

The Division contributes significantly to institutional, national and international collaborative research projects. Publications and conference abstracts from the Division cover a wide range of topics in infectious diseases, contributing to the understanding of infectious diseases in the South African context. 
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  • ?International Epidemiological Databases to Evaluate AIDS, Southern Africa. (IeDEA-SA. (HW Prozesky is the Local Principal Investigator and Member of the Steering Committee). Ongoing. For more info on IeDEA-SA: https://www.iedea-sa.org/

  • Implications of Severe COVID-19 at Tygerberg Hospital, Cape Town, South Africa. (Completed).

  • ?Protocol D822FC00001 (CALAVI): A Phase 2, Open Label, Randomized Study of the Efficacy and Safety of Acalabrutinib with Best Supportive Care Versus Best Supportive Care in Subjects Hospitalized With COVID-19. (HW Prozesky was the Local and National Principal Investigator). Completed.

  • Protocol ATR-002-202 (RESPIRE): Efficacy and safety of zapnometinib in hospitalised adult patients with COVID-19: A randomised, double-blind, placebo-controlled, multi-centre, proof of concept / phase 2 trial. (HW Prozesky was the Local and National Principal Investigator). Completed.

  • ACTG 5290 A Randomized, Phase 2b Study of a Double-Dose Lopinavir/Ritonavir-Based Antiretroviral Regimen with Rifampin-Based Tuberculosis Treatment versus a Standard-Dose Lopinavir/Ritonavir-Based Antiretroviral Regimen with Rifabutin-Based Tuberculosis Treatment with or without Raltegravir in HIV-1-Infected Persons Requiring Treatment for Active TB and HIV. (J Taljaard was Local PI) Completed.

  • GSK Clinical Trial – Protocol number: ING117175 Title: A Phase IIIb, randomized, open label study of the safety and efficacy of dolutegravir or efavirenz each administered with two NRTIs in HIV-1-infected ARV na?ve adults starting treatment for rifampicin-sensitive TB. (J Taljaard was Local PI) Completed.

  • AFREhealth COVID-19 and Pregnancy Research Collaboration Working Group. HW Prozesky, J Taljaard and A Parker were Co-Investigators. Completed.

  • Kaposi Sarcoma chemotherapy and research (KS-CARE) - Clinical and molecular determinants of HIV-associated Kaposi Sarcoma progression under local standard-of-care therapy in South Africa. (Z Ismail and HW Prozesky are Co-Investigators). Ongoing.

  • Tygerberg Endocarditis cohort Study (TEC). (J Taljaard and HW Prozesky were Co-Investigators). Completed.
  • Non-tuberculous mycobacterial infections at a tertiary care centre in South Africa - A retrospective case series. (The division are co-investigators and J Taljaard is the study leader). Ongoing.

  • Hepatitis B in Africa collaborative network (HEPSANET). (HW Prozesky is the Local Principal Investigator and T Lovelock, J Taljaard and M v Schalkwyk are co-investigators). Ongoing. For more info on HEPSANET: https://www.hepsanet.org/
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  • Protocol MHIPS-2020-001 (COLCORONA): Colchicine for community-treated patients with COVID-19: A phase 3, randomised, double-blinded, adaptive, placebo-controlled, multicentre trial. (HW Prozesky was the Local Principal Investigator). Completed.

?Peer-Reviewed Publications

  1. Saieva P, Lovelock T, Jardine T. Even a worm will turn: An atypical presentation of hydatid disease. S Afr J Infect Dis. 2024;39(1), a661. https://doi.org/10.4102/sajid.v39i1.661

  2. Boyles T, Berhanu RH, Gogela N, …Lovelock T, Parker A…et al. Management of drug-induced liver injury in people with HIV treated for tuberculosis: 2024 update. S Afr J HIV Med. 2024;25(1), a1558.? https://doi.org/10.4102/sajhivmed.v25i1.1558

  3. Mashigo B, Parker A, Lalla U, Allwood BW, Moolla MS, Lovelock T, Koegelenberg CFN. An outbreak within an outbreak: The impact of Infection Prevention and Control strategies on hospital-acquired infections and the occurrence of multi-drug-resistant organisms during the COVID-19 pandemic. S Afr Med J [Internet]. 2023 Dec. 4 [cited 2024 Oct. 21];113(12):42. Available from: https://samajournals.co.za/index.php/samj/article/view/971

  4. H Rabie, J Taljaard. Improving tuberculosis diagnosis in adults with HIV through urine Xpert MTB/RIF Ultra. The Lancet Global Health, 2024

  5. Minier N, Guingané AN, Okeke E, Sinkala E, Johannessen A, Andersson MI, Davwar P, Desalegn H, Duguru M, Fall F, Mboup S, Maponga T, Matthews PC, Ramírez Mena A, Ndow G, Orlien SMS, Riches N, Seydi M, Sonderup M, Spearman CW, Stockdale AJ, Taljaard J, Vinikoor M, Wandeler G, Lemoine M, Shimakawa Y, Sombié R. Development and evaluation of a simple treatment eligibility score (HEPSANET) to decentralise hepatitis B care in Africa: a cross-sectional study. Lancet Gastroenterol Hepatol. 2024 Apr;9(4):323-332. doi: 10.1016/S2468-1253(23)00449-1. Epub 2024 Feb 15. PMID: 38367633.

  6. Nyakato P, Schomaker M, Boulle A, Euvrard J, Wood R, Eley B, Prozesky HW, Christ B, Anderegg N, Ayakaka I, Rafael I, Kunzekwenyika C, Moore CB, Van Lettow M, Chimbetete C, Mbewe S,  Ballif M, Egger M, Yiannoutsos CT, Cornell M, Davies M-A. Correcting mortality estimates among children and youth on antiretroviral therapy in Southern Africa: a comparative analysis between a multi-country tracing study and linkage to a health information exchange. Trop Med Int Health. 2024;29:739–751. DOI: 10.1111/tmi.14030.

  7. Marion Delphin, Khadija Said Mohammed, Louise O Downs, Sheila F Lumley, Elizabeth Waddilove, Dorcas Okanda, Nadia Aliyan, Marije Van Schalkwyk, Motswedi Anderson, Ponsiano Ocama, Tongai Maponga, Judith Torimiro, Collins Iwuji, Thumbi Ndung'u, Philippa C Matthews, Jantjie Taljaard. Under-representation of the WHO African region in clinical trials of interventions against hepatitis B virus infection. Lancet Gastroenterol Hepatol. 2024 Febr9(4):383-392. ISSN 2468-1253, https://doi.org/10.1016/S2468-1253(23)00315-1.

  8. G U van Zyl, T Maponga, H Rabie, J Taljaard. The role of new hepatitis B vaccines in South Africa. S Afr Med J, 2024;114(2):e1473.

  9. Lovelock T, Du Plessis M, Van der Westhuizen C, Jansen J, Lawrence C, Parker A, Pecoraro AJK, Prozesky HW, Von Gottberg A, Taljaard JJ. Non-toxigenic Corynebacterium diphtheriae endocarditis: A cluster of five cases. S Afr J Infect Dis. 2024;39(1), a539. https://doi.org/10.4102/sajid.v39i1.539 

  10. Rhode G, Stenglein S, Prozesky H, Manudhane G, Sandulescu O, Bauer M, Overend T, Koch W, Neuschwander D, Plantz O, Torres A, Witzenrath M. Efficacy and safety of zapnometinib in hospitalised adult patients with COVID-19: A randomised, double-blind, placebo-controlled, multi-centre, proof of concept / phase 2 trial (RESPIRE). EClinicalMedicine. 2023 November; 65:102237. doi: 10.1016/j.eclinm.2023.102237. Online, ahead of print (2023/10/04).

  11. Moolla H, Davies M-A, Davies C, Euvrard J, Prozesky HW, Fox MP, Orrell C, Von Groote, P, Johnson LF. The effect of unplanned care interruptions on the mortality of adults resuming antiretroviral therapy in South Africa: a survival analysis. AIDS 2024, 38:1198–1205. DOI: 10.1097/QAD.0000000000003859. 

  12. A Parker, A G B Broadhurst, M S Moolla,L Amien, Ahmed, J J Taljaard, G Meintjes, P Nyasulu, C F N Koegelenberg. A point-prevalence study of body mass indices in HIV-positive and HIV-negative patients admitted to hospital with COVID-19 in South Africa. Afr J Thoracic Crit Care Med 2023;29(3):e660. doi.org/10.7196/AJTCCM.2023.v29i3.660

  13. Spearman, C.W., Andersson, M.I., Bright, B., Davwar, P.M., Desalegn, H., Guingane, A.N., Johannessen, A., Kabagambe, K., Lemoine, M., Matthews, P.C., Ndow, G., Riches, N., Shimakawa, Y., Sombié, R., Stockdale, A.J., Taljaard, J.J., Vinikoor, M.J., Wandeler, G., Okeke, E., Sonderup, M., and on behalf of the Hepatitis B in Africa Collaborative Network (HEPSANET). A new approach to prevent, diagnose, and treat hepatitis B in Africa. BMC Global Public Health 1, 24 (2023). https://doi.org/10.1186/s44263-023-00026-1

  14. Nicolas Minier, Asgeir Johannessen, Alice Guingané, Gilles Wandeler, Michael Vinikoor, Jantjie Taljaard, Alexander Stockdale, Wendy Spearman, Mark Sonderup, Roger Sombie, Edford Sinkala, Moussa Seydi, Nicholas Riches, Edith Okeke, Gibril Ndow, Adri Ramírez Mena, Philippa Matthews, Tongai Gibson Maponga, Hailemichael Desalegn, Fatou Fall, Monique Andersson, Maud Lemoine, Yusuke Shimakawa. Simple treatment eligibility score for chronic HBV infection at peripheral health facilities in sub-Saharan Africa. June 2023, Journal of Hepatology 78:S916. DOI: 10.1016/S0168-8278(23)02941-0.

  15. Riches N, Vinikoor M, Guingane A, Johannessen A, Lemoine M, Matthews P, Okeke E, Shimakawa Y, Sombie R, Stockdale A, Wandeler G, Andersson M, Davwar P, Desalegn H, Duguru M, Fall F, Maponga T, Nyam Paul D, Seydi M, Sinkala E, Taljaard J, Sonderup M, Spearman CW. Hepatitis B in Africa Collaborative Network: cohort profile and analysis of baseline data. Epidemiol Infect. 2023 Apr 3;151:e65. doi: 10.1017/S095026882300050X. PMID: 37009881; PMCID: PMC10204139.

  16. Van Schalkwyk M, Bekker A, Decloedt E, Wang J, Theron GB, Cotton MF, Eke AC, Cressey TR, Shapiro DE, Bacon K, Knowles K, George K, Browning R, Chakhtoura N, Rungruengthanakit K, Wiesner L, Capparelli EV, Stek AM, Mirochnick M, Best BM. Pharmacokinetics and safety of first-line tuberculosis drugs rifampin, isoniazid, ethambutol, and pyrazinamide during pregnancy and postpartum: results from IMPAACT P1026s. Antimicrob Agents Chemother. 2023 Nov 15;67(11):e0073723. doi: 10.1128/aac.00737-23. Epub 2023 Oct 26. PMID: 37882552; PMCID: PMC10648924.

  17. Du Plessis WP, Lahri S, Somers K, Lovelock T. Deeply jaundiced: Not so surgical after all. S Afr J Infect Dis. 2023;38(1), a559. https://doi.org/10.4102/sajid.v38i1.55

  18. Mcinziba A, Wademan D, Viljoen L, Myburgh H, Jennings L, Decloedt E, Orrell C, Van Zyl G, Van Schalkwyk M, Gandhi M, Hoddinott G. Perspectives of people living with HIV and health workers about a point-of-care adherence assay: a qualitative study on acceptability. AIDS CARE 2023 Oct;35(10):1628-1634. doi: 10.1080/09540121.2023.2174928. Epub 2023 Feb 13. PMID: 36781407; PMCID: PMC10423296.

  19. Agyemang N, Scarsi KK, Baker P, Smeaton LM, Podany AT, Olefsky M, Woolley E, Barr E, Pham M, Mawlana S, Supparatpinyo K, Gatechompol S, Jalil EM, Gadama L, Badal-Faesen S, Van Schalkwyk M, Kayama C, Belaunzaran-Zamudio PF, Godfrey C, Cohn SE, Mngqibisa R, Haas DW; Pharmacogenetic interactions of efavirenz or rifampin and isoniazid with levonorgestrel emergency contraception during treatment of HIV or tuberculosis. AIDS Clinical Trials Group A5375 Study Team. Pharmacogenet Genomics. 2023 Aug 1;33(6):126-135. doi: 10.1097/FPC.0000000000000501. Epub 2023 Jun 12. PMID: 37306344; PMCID: PMC10309098.

  20. Maugans C, Loveday M, Hlangu S, Waitt C, Van Schalkwyk M, van de Water B, Salazar-Austin N, McKenna L, Mathad JS, Kalk E, Hurtado R, Hughes J, Eke AC, Ahmed S, Furin J. Best practices for the care of pregnant people living with TB.  Int J Tuberc Lung Dis. 2023 May 1;27(5):357-366. doi: 10.5588/ijtld.23.0031. PMID: 37143222. 

  21. Van Zyl G, Jennings L, Kellermann T, Nkantsu Z, Cogill D, Van Schalkwyk M, Spinelli M, Decloedt E, Orrell C, Gandhi M. Urine tenofovir-monitoring predicts HIV viremia in patients treated with high genetic-barrier regimens. AIDS. 2022 Nov 15;36(14):2057-2062. doi: 10.1097/QAD.0000000000003354. Epub 2022 Aug 10. PMID: 36305182.

  22. Avihingsanon A, Hughes MD, Salata R, Godfrey C, McCarthy C, Mugyenyi P, Hogg E, Gross R, Cardoso SW, Bukuru A, Makanga M, Badal-Faesen S, Mave V, Ndege BW, Fontain SN, Samaneka W, Secours R, Van Schalkwyk M , Mngqibisa R , Mohapi L, Valencia J, Sugandhavesa P, Montalban E, Munyanga C, Chagomerana M, Santos BR, Kumarasamy N, Kanyama C, Schooley RT, Mellors JW, Wallis CL, Collier AC and Grinsztejn B for the A5288 Study team. 2022 Jun. Third-line antiretroviral therapy, including raltegravir (RAL), darunavir (DRV/r) and/or etravirine (ETR), is well tolerated and achieves durable virologic suppression over 144 weeks in resource-limited settings: ACTG A5288 strategy trial. J Int AIDS Soc., 25: e25905. doi:10.1002/jia2.25905. PMID: 36039892 PMCID: PMC9332128

  23. Solomon SS, Wagner-Cardoso S, Smeaton L, Sowah LA, Wimbish C, Robbins G, Brates I, Scello C, Son A, Avihingsanon A, Linas B, Anthony D, Nunes EP, Kliemann DA, Supparatpinyo K, Kityo C, Tebas P, Bennet JA, Santana-Bagur J, Benson CA, Van Schalkwyk M, Cheinquer N, Naggie S, Wyles D, Sulkowski M. A minimal monitoring approach for the treatment of hepatitis C virus infection (ACTG A5360 [MINMON]): a phase 4, open-label, single-arm trial. Lancet Gastroenterol Hepatol. 2022 Apr;7(4):307-317. doi: 10.1016/S2468-1253(21)00397-6. Epub 2022 Jan 10. PMID: 35026142. PMCID: PMC8920770.

  24. Jennings L, Kellerman T, Spinelli M, Nkantsu Z, Cogill D, van Schalkwyk M, Decloedt E, van Zyl G, Orrell C, Gandhi M. Drug resistance, rather than low tenofovir levels in blood or urine, is associated with tenofovir, emtricitabine and efavirenz (TEE) failure in resource-limited settings. AIDS Res Hum Retroviruses. 2022 Jun;38(6):455-462. doi: 10.1089/AID.2021.0135. Epub 2021 Dec 29. PMID: 34779228. PMCID: PMC9225825.

  25. Boulle A, Davies MA, ...van Schalkwyk M ...et.al, Risk factors for COVID-19 death in a population cohort study from the Western Cape Province, South Africa. Western Cape Department of Health in collaboration with the National Institute for Communicable Diseases, South Africa. Clin Infect Dis. 2021 Oct 5;73(7):e2005-e2015. doi: 10.1093/cid/ciaa1198. Erratum in: Clin Infect Dis. 2022 Apr 9;74(7):1321. PMID: 32860699; PMCID: PMC7499501.

  26. Kassanjee, R., Davies, M.-A., Ngwenya, O., Osei-Yeboah, R., Jacobs, T., Morden, E., Timmerman, V., Britz, S., Mendelson, M., Taljaard, J., Riou, J., Boulle, A., Tiffin, N. and Zinyakatira, N. (2023), COVID-19 among adults living with HIV: correlates of mortality among public sector healthcare users in Western Cape, South Africa. J Int AIDS Soc., 26: e26104. https://doi.org/10.1002/jia2.26104

  27. Mofokeng N, Maponga TG, van Schalkwyk M, Hugo S, Morobadi MD, Vawda S, Badenhorst L, van Vuuren C, van Rensburg C, Preiser W, Taljaard J, Wang S, Miller V, Wu D, Tucker JD, Seeley J, Goedhals D, Matthews PC. Barriers that prevent adults living with HBV infection from participating in clinical research: experience from South Africa. J Virus Erad. 2023 Feb 23;9(1):100317. doi: 10.1016/j.jve.2023.100317. PMID: 36911657; PMCID: PMC9995934.

  28. Johannessen A, Stockdale AJ, Henrion MYR, Okeke E, Seydi M, Wandeler G, Sonderup M, Spearman CW, Vinikoor M, Sinkala E, Desalegn H, Fall F, Riches N, Davwar P, Duguru M, Maponga T, Taljaard J, Matthews PC, Andersson M, Mboup S, Sombie R, Shimakawa Y, Lemoine M. Systematic review and individual-patient-data meta-analysis of non-invasive fibrosis markers for chronic hepatitis B in Africa. Nat Commun. 2023 Jan 3;14(1):45. doi: 10.1038/s41467-022-35729-w. PMID: 36596805; PMCID: PMC9810658.

  29. Peter S. Nyasulu, Birhanu T. Ayele, Coenraad F. Koegelenberg, Elvis Irusen, Usha Lalla, Razeen Davids, Yazied Chothia, Francois RetiefI, Marianne Johnson, Stephen Venter, Renilda Pillay, Hans Prozesky, Jantjie Taljaard, Arifa Parker, Eric H. Decloedt, Portia Jordan, Sa’ad Lahri, M Rafique Moosa, Muhammad Saadiq MoollaI, Anteneh Yalew, Nicola Baines, Padi Maud, Elizabeth Louw,Andre Nortje, Rory Dunbar, Lovemore N. SigwadhiI, Veranyuy, Ngah, Jacques L. TamuziI, Annalise Zemlin, Zivanai Chapanduka, Rene ? English, BrianW. Allwood. Clinical characteristics associated with mortality of COVID-19 patients admitted to an intensive care unit of a tertiary hospital in South Africa. December 2022. PLoS ONE 17(12):e0279565. DOI: 10.1371/journal.pone.0279565

  30. Davies MA, Morden E, Rosseau P, Arendse J, Bam JL, Boloko L, Cloete K, Cohen C, Chetty N, Dane P, Heekes A, Hsiao NY, Hunter M, Hussey H, Jacobs T, Jassat W, Kariem S, Kassanjee R, Laenen I, Roux SL, Lessells R, Mahomed H, Maughan D, Meintjes G, Mendelson M, Mnguni A, Moodley M, Murie K, Naude J, Ntusi NAB, Paleker M, Parker A, Pienaar D, Preiser W, Prozesky H, Raubenheimer P, Rossouw L, Schrueder N, Smith B, Smith M, Solomon W, Symons G, Taljaard J, Wasserman S, Wilkinson RJ, Wolmarans M, Wolter N, Boulle A. Outcomes of laboratory-confirmed SARS-CoV-2 infection during resurgence driven by Omicron lineages BA.4 and BA.5 compared with previous waves in the Western Cape Province, South Africa. Int J Infect Dis. 2022 Nov 24:S1201-9712(22)00615-4. doi: 10.1016/j.ijid.2022.11.024.

  31. Pecoraro AJK, Herbst PG, Janson JT, Wagenaar R, Ismail Z, Taljaard JJ, Prozesky HW, Pienaar C, Doubell AF. Early surgery determines prognosis in patients with infective endocarditis: outcome in patients managed by an Endocarditis Team-a prospective cohort study. Cardiovasc Diagn Ther. 2022 Aug;12(4):453-463. doi: 10.21037/cdt-21-590. PMID: 36033220; PMCID: PMC9412218.

  32. Asgeir Johannessen, Alexander J. Stockdale, Marc Y.R. Henrion, Edith Okeke, Moussa Seydi, Gilles Wandeler, Mark Sonderup, C. Wendy Spearman, Michael Vinikoor, Edford Sinkala, Hailemichael Desalegn, Fatou Fall, Nicholas Riches, Pantong Davwar, Mary Duguru, Tongai Maponga, Jantjie Taljaard, Philippa C. Matthews, Monique Andersson, Roger Sombie, Yusuke Shimakawa, Maud Lemoine. Diagnostic performance of non-invasive fibrosis markers for chronic hepatitis B in sub-Saharan Africa: a Bayesian individual patient data meta-analysis. Journal of Hepatology, July 2022; 77:S23-S24. DOI: 10.1016/S0168-8278(22)00461-5

  33. Susan Meiring, Stefano Tempia, Jinal N Bhiman, Amelia Buys, Jackie Kleynhans, Mvuyo Makhasi, Meredith McMorrow, Jocelyn Moyes, Vanessa Quan, Sibongile Walaza, Mignon du Plessis, Nicole Wolter, Anne von Gottberg, Cheryl Cohen, COVID-19 shedding study group. Prolonged Shedding of Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at High Viral Loads Among Hospitalized Immunocompromised Persons Living With Human Immunodeficiency Virus (HIV), South Africa, Clinical Infectious Diseases, Volume 75, Issue 1, 1 July 2022, Pages e144–e156, https://doi.org/10.1093/cid/ciac077

  34. Parker A, Boloko L, Moolla MS, Ebrahim N, Ayele BT, Broadhurst AGB, Mashigo B, Titus G, de Wet T, Boliter N, Rosslee MJ, Papavarnavas N, Abrahams R, Mendelson M, Dlamini S, Taljaard JJ, Prozesky HW, Mowlana A, Viljoen AJ, Schrueder N, Allwood BW, Lalla U, Dave JA, Calligaro G, Levin D, Maughan D, Ntusi NAB, Nyasulu PS, Meintjes G, Koegelenberg CFN, Mnguni AT, Wasserman S. Clinical features and outcomes of COVID-19 admissions in a population with a high prevalence of HIV and tuberculosis: a multicentre cohort study. BMC Infect Dis. 2022 Jun 20;22(1):559. doi: 10.1186/s12879-022-07519-8.PMID: 35725387

  35. Davies MA, Kassanjee R, Rousseau P, Morden E, Johnson L, Solomon W, Hsiao NY, Hussey H, Meintjes G, Paleker M, Jacobs T, Raubenheimer P, Heekes A, Dane P, Bam JL, Smith M, Preiser W, Pienaar D, Mendelson M, Naude J, Schrueder N, Mnguni A, Le Roux S, Murie K, Prozesky H, Mahomed H, Rossouw L, Wasserman S, Maughan D, Boloko L, Smith B, Taljaard J, Symons G, Ntusi NAB, Parker A, Wolter N, Jassat W, Cohen C, Lessells R, Wilkinson RJ, Arendse J, Kariem S, Moodley M, Wolmarans M, Cloete K, Boulle A; Western Cape and South African National Departments of Health in collaboration with the National Institute for Communicable Diseases in South Africa Affiliations. Outcomes of laboratory-confirmed SARS-CoV-2 infection in the Omicron-driven fourth wave compared with previous waves in the Western Cape Province, South Africa. Trop Med Int Health. 2022 Jun;27(6):564-573. doi: 10.1111/tmi.13752. PMID: 35411997

  36. Jean B. Nachega, Nadia A. Sam-Agudu, Rhoderick N. Machekano, Philip J. Rosenthal, Sonja Schell, Liesl de Waard, Adrie Bekker, Onesmus W. Gachuno, John Kinuthia, Nancy Mwongeli, Samantha Budhram, Valerie Vannevel, Priya Somapillay, Hans W. Prozesky, Jantjie Taljaard, Arifa Parker, Elizabeth Agyare, Akwasi Baafuor Opoku, Aminatu Umar Makarfi, Asara M. Abdullahi, Chibueze Adirieje, Daniel Katuashi Ishoso, Michel Tshiasuma Pipo, Marc B. Tshilanda, Christian Bongo-Pasi Nswe, John Ditekemena, Lovemore Nyasha Sigwadhi, Peter S. Nyasulu, Michel P. Hermans, Musa Sekikubo, Philippa Musoke, Christopher Nsereko, Evans K. Agbeno, Michael Yaw Yeboah, Lawal W. Umar, Mukanire Ntakwinja, Denis M. Mukwege, Etienne Kajibwami Birindwa, Serge Zigabe Mushamuka, Emily R. Smith, Edward J. Mills, John Otokoye Otshudiema, Placide Mbala-Kingebeni, Jean-Jacques Muyembe Tamfum, Alimuddin Zumla, Aster Tsegaye, Alfred Mteta, Nelson K. Sewankambo, Fatima Suleman, Prisca Adejumo, Jean R. Anderson, Emilia V. Noormahomed, Richard J. Deckelbaum, Jeffrey S. A. Stringer, Abdon Mukalay, Taha E. Taha, Mary Glenn Fowler, Judith N. Wasserheit, Refiloe Masekela, John W. Mellors, Mark J. Siedner, Landon Myer, Andre-Pascal Kengne, Marcel Yotebieng, Lynne M. Mofenson, Eduard Langenegger, for the AFREhealth Research Collaboration on COVID-19 and Pregnancy, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and Pregnancy in Sub-Saharan Africa: A 6-Country Retrospective Cohort Analysis, Clinical Infectious Diseases, 2022;, ciac294, https://doi.org/10.1093/cid/ciac294

  37. Smit L, Redfern A, Murray S, Lishman J, van der Zalm MM, van Zyl G, Verhagen LM, de Vos C, Rabie H, Dyk A, Claassen M, Taljaard J, Aucamp M, Dramowski A. SARS-CoV-2 in children and their accompanying caregivers: Implications for testing strategies in resource limited hospitals. Afr J Emerg Med. 2022 Sep;12(3):177-182. doi: 10.1016/j.afjem.2022.04.007. Epub 2022 Apr 25. PMID: 35496826 

  38. Van Rensburg R, Nightingale S, Brey N, Albertyn CH, Kellermann TA, Taljaard JJ, Esterhuizen T, Sinxadi PZ, Decloedt EH. Pharmacogenetics of the Late-Onset Efavirenz Neurotoxicity Syndrome (LENS). Clinical Infectious Diseases 2022; 75(3):399-405.

  39. V Pillay-Fuentes Lorente, R van Rensburg, MS Moolla, M McCaul, A Parker, J Taljaard, H Reuter, EH Decloedt.  Bleeding and thrombosis outcomes in hospitalised COVID 19 patients on low-molecular-weight heparin and antiplatelet therapy. S Afr Med J 2022;112(7):472-477. https://doi.org/10.7196/SAMJ.2022.v112i7.16434.

  40. A Engelbrecht, C van der Westhuizen, J J Taljaard. Rationalizing empiric antibiotics for bloodstream infections: A retrospective study at a South African district-level hospital. South African Medical Journal 2022;112(1):27-33.

  41. Pecoraro AJK, Herbst PG, Pienaar C, Taljaard J, Prozesky H, Janson J, Doubell AF. Modified Duke/European Society of Cardiology 2015 clinical criteria for infective endocarditis: time for an update? Open Heart. 2022 May;9(1):e001856. doi: 10.1136/openhrt-2021-001856. PMID: 35534094 

  42. Pecoraro AJK, Pienaar C, Herbst PG, Poerstamper S, Joubert L, Taljaard J, Prozesky H, Janson J, Newton-Foot M, Doubell AF. Causes of infective endocarditis in the Western Cape, South Africa: a prospective cohort study using a set protocol for organism detection and central decision making by an endocarditis team. BMJ Open. 2021 Dec 6;11(12):e053169. doi: 10.1136/bmjopen-2021-053169. PMID: 34873007 

  43. Lalla U, Koegelenberg CFN, Allwood BW, Sigwadhi LN, Irusen EM, Zemlin AE, Masha TE, Erasmus RT, Chapanduka ZC, Prozesky H, Taljaard J, Parker A, Decloedt EH, Retief F, Jalavu TP, Ngah VD, Yalew A, Tamuzi JL, Baines N, McAllister M, Zumla A, Nyasulu PS. Comparison of patients with severe COVID-19 admitted to an intensive care unit in South Africa during the first and second wave of the COVID-19 pandemic. Afr J Thorac Crit Care Med. 2021 Dec 31;27(4):10.7196/AJTCCM.2021.v27i4.185. doi: 10.7196/AJTCCM.2021.v27i4.185. PMID: 35359698; PMCID: PMC8948479.

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  95. 95. Nachega JB, Fatti G, Zumla A, Geng EH. The where, when, and how of community-based versus clinic-based ART delivery in South Africa and Uganda. Lancet Glob Health. 2020 Oct;8(10):e1245-e1246. doi: 10.1016/S2214-109X(20)30385-5. PMID: 32971045; PMCID: PMC7505575.

  96. 96. Nachega JB, Ishoso DK, Otokoye JO, Hermans MP, Machekano RN, Sam-Agudu NA, Bongo-Pasi Nswe C, Mbala-Kingebeni P, Madinga JN, Mukendi S, Kolié MC, Nkwembe EN, Mbuyi GM, Nsio JM, Mukeba Tshialala D, Tshiasuma Pipo M, Ahuka-Mundeke S, Muyembe-Tamfum JJ, Mofenson L, Smith G, Mills EJ, Mellors JW, Zumla A, Mavungu Landu DJ, Kayembe JM. Clinical Characteristics and Outcomes of Patients Hospitalized for COVID-19 in Africa: Early Insights from the Democratic Republic of the Congo. Am J Trop Med Hyg. 2020 Dec;103(6):2419-2428. doi: 10.4269/ajtmh.20-1240. Epub 2020 Oct 2. PMID: 33009770; PMCID: PMC7695108.

  97. Nachega JB, Sam-Agudu NA, Budhram S, Taha TE, Vannevel V, Somapillay P, Ishoso DK, Tshiasuma Pipo M, Bongo-Pasi Nswe C, Ditekemena J, Ayele BT, Machekano RN, Gachuno OW, Kinuthia J, Mwongeli N, Sekikubo M, Musoke P, Agbeno EK, Umar LW, Ntakwinja M, Mukwege DM, Smith ER, Mills EJ, Otshudiema JO, Mbala-Kingebeni P, Kayembe JN, Mavungu Landu DJ, Muyembe Tamfum JJ, Zumla A, Langenegger EJ, Mofenson LM, For The AFREhealth Covid-Research Collaboration Working Group. Effect of SARS-CoV-2 Infection in Pregnancy on Maternal and Neonatal Outcomes in Africa: An AFREhealth Call for Evidence through Multicountry Research Collaboration. Am J Trop Med Hyg. 2020 Dec 28;104(2):461–5. doi: 10.4269/ajtmh.20-1553. Epub ahead of print. PMID: 33372651; PMCID: PMC7866362.

  98. Lee Z, Rayner CR, Forrest JI, Nachega JB, Senchaudhuri E, Mills EJ. The Rise and Fall of Hydroxychloroquine for the Treatment and Prevention of COVID-19. Am J Trop Med Hyg. 2021 Jan;104(1):35-38. doi: 10.4269/ajtmh.20-1320. PMID: 33236703; PMCID: PMC7790108.

  99. Nachega JB, Grimwood A, Mahomed H, Fatti G, Preiser W, Kallay O, Mbala PK, Muyembe JT, Rwagasore E, Nsanzimana S, Ngamije D, Condo J, Sidat M, Noormahomed EV, Reid M, Lukeni B, Suleman F, Mteta A, Zumla A. From Easing Lockdowns to Scaling Up Community-based Coronavirus Disease 2019 Screening, Testing, and Contact Tracing in Africa-Shared Approaches, Innovations, and Challenges to Minimize Morbidity and Mortality. Clin Infect Dis. 2021 Jan 27;72(2):327-331. doi: 10.1093/cid/ciaa695. PMID: 33501963; PMCID: PMC7314180.

  100. Nachega JB, Atteh R, Ihekweazu C, Sam-Agudu NA, Adejumo P, Nsanzimana S, Rwagasore E, Condo J, Paleker M, Mahomed H, Suleman F, Ario AR, Kiguli-Malwadde E, Omaswa FG, Sewankambo NK, Viboud C, Reid MJA, Zumla A, Kilmarx PH. Contact Tracing and the COVID-19 Response in Africa: Best Practices, Key Challenges, and Lessons Learned from Nigeria, Rwanda, South Africa, and Uganda. Am J Trop Med Hyg. 2021 Feb 11;104(4):1179–87. doi: 10.4269/ajtmh.21-0033. Epub ahead of print. PMID: 33571138; PMCID: PMC8045625.

  101. Sam-Agudu NA, Rabie H, Pipo MT, Byamungu LN, Masekela R, van der Zalm MM, Redfern A, Dramowski A, Mukalay A, Gachuno OW, Mongweli N, Kinuthia J, Ishoso DK, Amoako E, Agyare E, Agbeno EK, Jibril AM, Abdullahi AM, Amadi O, Umar UM, Ayele BT, Machekano RN, Nyasulu PS, Hermans MP, Otshudiema JO, Bongo-Pasi Nswe C, Kayembe JN, Mbala-Kingebeni P, Muyembe-Tamfum JJ, Aanyu HT, Musoke P, Fowler MG, Sewankambo N, Suleman F, Adejumo P, Tsegaye A, Mteta A, Noormahomed EV, Deckelbaum RJ, Zumla A, Mavungu Landu DJ, Tshilolo L, Zigabe S, Goga A, Mills EJ, Umar LW, Kruger M, Mofenson LM, Nachega JB; for investigators in the AFREhealth COVID-19 Research Collaboration on Children and Adolescents. The Critical Need for Pooled Data on COVID-19 in African Children: An AFREhealth Call for Action through Multi-Country Research Collaboration. Clin Infect Dis. 2021 Feb 13:ciab142. doi: 10.1093/cid/ciab142. Epub ahead of print. PMID: 33580256; PMCID: PMC7929059.

  102. Ditekemena JD, Nkamba DM, Mutwadi A, Mavoko HM, Siewe Fodjo JN, Luhata C, Obimpeh M, Van Hees S, Nachega JB, Colebunders R. COVID-19 Vaccine Acceptance in the Democratic Republic of Congo: A Cross-Sectional Survey. Vaccines (Basel). 2021 Feb 14;9(2):153. doi: 10.3390/vaccines9020153. PMID: 33672938; PMCID: PMC7917589.

  103. Katoto PDMC, Kayembe-Kitenge T, Pollitt KJG, Martens DS, Ghosh M, Nachega JB, Nemery B, Nawrot TS. Telomere length and outcome of treatment for pulmonary tuberculosis in a gold mining community. Sci Rep. 2021 Feb 17;11(1):4031. doi: 10.1038/s41598-021-83281-2. PMID: 33597559; PMCID: PMC7889934.

  104. Nachega JB, Sam-Agudu NA, Masekela R, van der Zalm MM, Nsanzimana S, Condo J, Ntoumi F, Rabie H, Kruger M, Wiysonge CS, Ditekemena JD, Chirimwami RB, Ntakwinja M, Mukwege DM, Noormahomed E, Paleker M, Mahomed H, Tamfum JM, Zumla A, Suleman F. Addressing challenges to rolling out COVID-19 vaccines in African countries. Lancet Glob Health. 2021 Mar 10:S2214-109X(21)00097-8. doi: 10.1016/S2214-109X(21)00097-8. Epub ahead of print. PMID: 33713633; PMCID: PMC7946417.

  105. Chakaya J, Khan M, Ntoumi F, Aklillu E, Fatima R, Mwaba P, Kapata N, Mfinanga S, Hasnain SE, Katoto PDMC, Bulabula ANH, Sam-Agudu NA, Nachega JB, Tiberi S, McHugh TD, Abubakar I, Zumla A. Global Tuberculosis Report 2020 - Reflections on the Global TB burden, treatment and prevention efforts. Int J Infect Dis. 2021 Mar 11:S1201-9712(21)00193-4. doi: 10.1016/j.ijid.2021.02.107. Epub ahead of print. PMID: 33716195.

  106. Nachega JB, Borre ED, Dowdy DW, Chanda-Kapata P, Cleary S, Geng EH. Cost- effectiveness of universal HIV testing and treatment: where next? Lancet Glob Health. 2021 May;9(5):e573-e574. doi: 10.1016/S2214-109X(21)00089-9. Epub 2021 Mar 12. PMID: 33721567.

  107. Zumla A, Chakaya J, Khan M, Fatima R, Wejse C, Al-Abri S, Fox GJ, Nachega J, Kapata N, Knipper M, Orcutt M, Goscé L, Abubakar I, Nagu TJ, Mugusi F, Gordon AK, Shanmugam S, Bachmann NL, Lam C, Sintchenko V, Rudolf F, Amanullah F, Kock R, Haider N, Lipman M, King M, Maeurer M, Goletti D, Petrone L, Yaqoob A, Tiberi S, Ditiu L, Sahu S, Marais B, Issayeva AM, Petersen E. World Tuberculosis Day 2021 Theme - 'The Clock is Ticking' - and the world is running out of time to deliver the United Nations General Assembly commitments to End TB due to the COVID-19 pandemic. Int J Infect Dis. 2021 Mar 18:S1201-9712(21)00264-2. doi: 10.1016/j.ijid.2021.03.046. Epub ahead of print. PMID: 33746094.

  108. Nachega JB, Kapata N, Sam-Agudu NA, Decloedt EH, Katoto PDMC, Nagu T, Mwaba P, Yeboah-Manu D, Chanda-Kapata P, Ntoumi F, Geng EH, Zumla A. Minimizing the impact of the triple burden of COVID-19, tuberculosis and HIV on health services in sub-Saharan Africa. Int J Infect Dis. 2021 Mar 20:S1201-9712(21)00256-3. doi: 10.1016/j.ijid.2021.03.038. Epub ahead of print. PMID: 33757874; PMCID: PMC7980520.

  109. Nachega JB, Maeurer M, Sam-Agudu NA, Chakaya J, Katoto PDM, Zumla A. Bacille Calmette-Guérin (BCG) vaccine and potential cross-protection against SARS-CoV-2 infection - Assumptions, knowns, unknowns and need for developing an accurate scientific evidence base. Int J Infect Dis. 2021 Mar 29:S1201-9712(21)00279-4. doi: 10.1016/j.ijid.2021.03.060. Epub ahead of print. PMID: 33794380; PMCID: PMC8006492.

  110. Nachega JB, Sam-Agudu NA, Mellors JW, Zumla A, Mofenson LM. Scaling Up 中国体育彩票 Vaccination in Africa - Lessons from the HIV Pandemic. N Engl J Med. 2021 Mar 31. doi: 10.1056/NEJMp2103313. Epub ahead of print. PMID: 33789005.

  111. Park JJH, Grais RF, Taljaard M, Nakimuli-Mpungu E, Jehan F, Nachega JB, Ford N, Xavier D, Kengne AP, Ashorn P, Socias ME, Bhutta ZA, Mills EJ. Urgently seeking efficiency and sustainability of clinical trials in global health. Lancet Glob Health. 2021 May;9(5):e681-e690. doi: 10.1016/S2214 109X(20)30539-8. PMID: 33865473.

  112. Park JJH, Mogg R, Smith GE, Nakimuli-Mpungu E, Jehan F, Rayner CR, Condo J, Decloedt EH, Nachega JB, Reis G, Mills EJ. How COVID-19 has fundamentally changed clinical research in global health. Lancet Glob Health. 2021 May;9(5):e711-e720. doi: 10.1016/S2214-109X(20)30542-8. PMID: 33865476; PMCID: PMC8049590.

  113. Bisimwa BC, Nachega JB, Warren RM, Theron G, Metcalfe JZ, Shah M, Diacon AH, Sam-Agudu NA, Yotebieng M, Bulabula ANH, Katoto PDMC, Chirambiza JP, Nyota R, Birembano FM, Musafiri EM, Byadunia S, Bahizire E, Kaswa MK, Callens S, Kashongwe ZM. Xpert Mycobacterium tuberculosis/Rifampicin-Detected Rifampicin Resistance is a Suboptimal Surrogate for Multidrug-resistant Tuberculosis in Eastern Democratic Republic of the Congo: Diagnostic and Clinical Implications. Clin Infect Dis. 2021 Jul 15;73(2):e362-e370. doi: 10.1093/cid/ciaa873

  114. Nachega JB, Sam-Agudu NA, Mellors JW, Zumla A, Mofenson LM. N Engl J Med. 2021 Jul 15;385(3):196-198. doi: 10.1056/NEJMp2103313. Epub 2021 Mar 31

  115. Sam-Agudu NA, Rabie H, Pipo MT, Byamungu LN, Masekela R, van der Zalm MM, Redfern A, Dramowski A, Mukalay A, Gachuno OW, Mongweli N, Kinuthia J, Ishoso DK, Amoako E, Agyare E, Agbeno EK, Mohammed Jibril A, Abdullahi AM, Amadi O, Mohammed Umar U, Ayele BT, Machekano RN, Nyasulu PS, Hermans MP, Otshudiema JO, Bongo-Pasi Nswe C, Kayembe JN, Mbala-Kingebeni P, Muyembe-Tamfum JJ, Aanyu HT, Musoke P, Fowler MG, Sewankambo N, Suleman F, Adejumo P, Tsegaye A, Mteta A, Noormahomed EV, Deckelbaum RJ, Zumla A, Mavungu Landu DJ, Tshilolo L, Zigabe S, Goga A, Mills EJ, Umar LW, Kruger M, Mofenson LM, Nachega JB; Investigators in the AFREhealth COVID-19 Research Collaboration on Children and Adolescents. The Critical Need for Pooled Data on Coronavirus Disease 2019 in African Children: An AFREhealth Call for Action Through Multicountry Research Collaboration. Clin Infect Dis. 2021 Nov 16;73(10):1913-1919. doi: 10.1093/cid/ciab142.

  116. Eichbaum Q, Sam-Agudu NA, Kazembe A, Kiguli-Malwadde E, Khanyola J, Wasserheit JN, Kilmarx PH, Nachega JB. Opportunities and Challenges in North-South and South-South Global Health Collaborations During the COVID-19 Pandemic: The AFREhealth-CUGH Experience (as Reported at the CUGH 2021 Satellite Meeting). Ann Glob Health. 2021 Sep 9;87(1):90. doi: 10.5334/aogh.3440. eCollection 2021.

  117. Robbertse PS, Doubell AF, Nachega JB, Herbst PG. The hidden continuum of HIV-associated cardiomyopathy: A focussed review with case reports. SA Heart J. 2021 Oct 27;18(2):126-135.

  118. Nachega, J.B., Sam-Agudu, N.A., Machekano, R.N., Rabie, H., van der Zalm, M.M., Redfern, A., Dramowski, A., O’Connell, N., Pipo, M.T., Tshilanda, M.B., Byamungu, L.N., Masekela, R., Jeena, P.M., Pillay, A., Gachuno, O.W., Kinuthia, J., Ishoso, D.K., Amoako, E., Agyare, E., Agbeno, E.K., Martyn-Dickens, C., Sylverken, J., Enimil, A., Jibril, A.M., Abdullahi, A.M., Amadi, O., Umar, U.M., Sigwadhi, L.N., Hermans, M.P., Otokoye, J.O., Mbala-Kingebeni, P., Muyembe-Tamfum, J.J., Zumla, A., Sewankambo, N.K., Aanyu, H.T., Musoke, P., Suleman, F., Adejumo, P., Noormahomed, E.V., Deckelbaum, R.J., Fowler, M.G., Tshilolo L., Smith, G., Mills, E.J., Umar, L.W., Siedner, M.J., Kruger, M., Rosenthal, P.J., Mellors, J.W., Mofenson. L.M.; African Forum for Research and Education in Health (AFREhealth) COVID-19 Research Collaboration on Children and Adolescents (2021). Assessment of Clinical Outcomes Among Children and Adolescents Hospitalized with COVID-19 in 6 Sub-Saharan African Countries. JAMA Pediatrics, 176(3), e216436. PMCID: PMC8771438

  119. Nachega J.B., Sam-Agudu NA, Siedner MJ, et al. (2022) Prioritizing Pregnant Women for Coronavirus Disease 2019 Vaccination in African Countries. Clin Infect Dis. Epub June 8, 2022

  120. Petersen E, Ntoumi F, Hui DS, Abubakar A, Kramer LD, Obiero C, Tambyah PA, Blumberg L, Yapi R, Al-Abri S, Pinto TCA, Yeboah-Manu D, Haider N, Asogun D, Velavan TP, Kapata N, Bates M, Ansumana R, Montaldo C, Mucheleng'anga L, Tembo J, Mwaba P, Himwaze CM, Hamid MMA, Mfinanga S, Mboera L, Raj T, Aklillu E, Veas F, Edwards S, Kaleebu P, McHugh TD, Chakaya J, Nyirenda T, Bockarie M, Nyasulu PS, Wejse C, Muyembe-Tamfum JJ, Azhar EI, Maeurer M, Nachega JB, Kock R, Ippolito G, Zumla A. Emergence of new SARS-CoV-2 Variant of Concern Omicron (B.1.1.529) - highlights Africa's research capabilities, but exposes major knowledge gaps, inequities of vaccine distribution, inadequacies in global COVID-19 response and control efforts. Int J Infect Dis. 2022 Jan;114:268-272. doi: 10.1016/j.ijid.2021.11.040. Epub 2021 Dec 1.

  121. Ntoumi F, Nachega JB, Aklillu E, Chakaya J, Felker I, Amanullah F, Yeboah-Manu D, Castro KG, Zumla A.Lancet Infect Dis. 2022 Apr;22(4):442-444. doi: 10.1016/S1473-3099(22)00142-6. Epub 2022 Mar 3. World Tuberculosis Day 2022: aligning COVID-19 and tuberculosis innovations to save lives and to end tuberculosis.

  122. Sam-Agudu NA, Quakyi NK, Masekela R, Zumla A, Nachega JB. Children and adolescents in African countries should also be vaccinated for COVID-19. BMJ Glob Health. 2022 Feb;7(2):e008315. doi: 10.1136/bmjgh-2021-00831

  123. Chanda-Kapata P, Ntoumi F, Kapata N, Lungu P, Mucheleng'anga LA, Chakaya J, Tembo J, Himwaze C, Ansumana R, Asogun D, Mfinanga S, Nyasulu P, Mwaba P, Yeboah-Manu D, Zumla A, Nachega JB. Tuberculosis, HIV/AIDS and Malaria Health Services in sub-Saharan Africa - A Situation Analysis of the Disruptions and Impact of the COVID-19 Pandemic.Int J Infect Dis. 2022 Mar 25:S1201-9712(22)00173-4. doi: 10.1016/j.ijid.2022.03.033. Online ahead of print

  124. Nachega JB, Machekano RN, Mofenson LM. The Need to Study Clinical Outcomes in Children and Adolescents With COVID-19 From Middle- and Low-Income Regions. JAMA Pediatr. 2022 May 9. doi: 10.1001/jamapediatrics.2022.1162. Online ahead of print

  125. Bepouka B, Situakibanza H, Sangare M, Mandina M, Mayasi N, Longokolo M, Odio O, Mangala D, Isekusu F, Kayembe JM, Nachega J, Mbula M. Mortality associated with COVID-19 and hypertension in sub-Saharan Africa. A systematic review and meta-analysis. J Clin Hypertens (Greenwich). 2022 Feb;24(2):99-105. doi: 10.1111/jch.14417. Epub 2022 Jan 27

  126. Nsanzimana S, Rawat A, Wilson LA, Forrest JI, …Nachega JB et al. Toward a New Paradigm of North-South and South-South Partnerships for Pandemic Preparedness: Lessons Learned from COVID-19 and Other Outbreaks. Am J Trop Med Hyg. 2022 Nov 14;107(6):1162-1165.

  127. Noormahomed EV, Noormahomed S, Hlashwayo D, Martins E, Ismail M, Bickler SW, Nachega J, Mahoche M, Barrett KE, Benson CA, Schooley RT. Fostering Sustainable Biomedical Research Training in Mozambique: A Spin-Off of the Medical Education Partnership Initiative. Ann Glob Health. 2022 Aug 2;88(1):65. doi: 10.5334/aogh.3684. eCollection 2022

  128. Nakimuli-Mpungu E, Smith CM, Wamala K, …Nachega JB et al. Long-Term Effect of Group Support Psychotherapy on Depression and HIV Treatment Outcomes: Secondary Analysis of a Cluster Randomized Trial in Uganda. Psychosom Med. 2022 Oct 1;84(8):914-923.

  129. Smith ER, Oakley E, He S, Zavala R,…Nachega JB, et al. Protocol for a sequential, prospective meta-analysis to describe coronavirus disease 2019 (COVID-19) in the pregnancy and postpartum periods. PLoS One. 2022 Jun 16;17(6):e0270150.

  130. Ntoumi F, Nachega JB, Aklillu E, et al. World Tuberculosis Day 2022: aligning COVID-19 and tuberculosis innovations to save lives and to end tuberculosis. Lancet Infect Dis. 2022 Apr;22(4):442-444. doi: 10.1016/S1473-3099(22)00142-6. Epub 2022 Mar 3. PMID: 35248166 Free PMC article. No abstract available.

  131. Petersen E, Zumla A, …Nachega JB et al. Vaccination for monkeypox prevention in persons with high-risk sexual behaviours to control on-going outbreak of monkeypox virus clade 3. Int J Infect Dis. 2022 Sep; 122:569-571. doi: 10.1016/j.ijid.2022.06.047. Epub 2022 Jul 2. PMID: 35788415 Free PMC article. No abstract available.

  132. ?Nachega JB, Nsanzimana S, Rawat A, Wilson LA, Rosenthal PJ, Siedner MJ, Varma JK, Kilmarx PH, Mutesa L, Tanner M, Binagwaho A, Forrest J, Mbala-Kingebeni P, Muyembe-Tamfum JJ, Ntoumi F, Zumla A, de Oliveira T, Mills EJ. Advancing detection and response capacities for emerging and re-emerging pathogens in Africa. Lancet Infect Dis. 2022 Dec 20:S1473-3099(22)00723-X.

  133. Smith ER, Oakley E, Grandner GW, Ferguson K, Farooq F, Afshar Y, Ahlberg M, Ahmadzia H, Akelo V, Aldrovandi G, Tippett Barr BA, Bevilacqua E, Brandt JS, Broutet N, Fernández Buhigas I, Carrillo J, Clifton R, Conry J, Cosmi E, Crispi F, Crovetto F, Delgado-López C, Divakar H, Driscoll AJ, Favre G, Flaherman VJ, Gale C, Gil MM, Gottlieb SL, Gratacós E, Hernandez O, Jones S, Kalafat E, Khagayi S, Knight M, Kotloff K, Lanzone A, Le Doare K, Lees C, Litman E, Lokken EM, Laurita Longo V, Madhi SA, Magee LA, Martinez-Portilla RJ, McClure EM, Metz TD, Miller ES, Money D, Moungmaithong S, Mullins E, Nachega JB, et al.; Adverse maternal, fetal, and newborn outcomes among pregnant women with SARS-CoV-2 infection: an individual participant data meta-analysis. BMJ Glob Health. 2023 Jan;8(1):e009495. Perinatal COVID PMA Study Collaborators; Perinatal COVID PMA Study Collaborators. BMJ Glob Health. 2023 Jan;8(1):e009495.

  134. Smith ER, Oakley E, Grandner GW, Rukundo G, Farooq F, Ferguson K, Baumann S, Adams Waldorf KM, Afshar Y, Ahlberg M, Ahmadzia H, Akelo V, Aldrovandi G, Bevilacqua E, Bracero N, Brandt JS, Broutet N, Carrillo J, Conry J, Cosmi E, Crispi F, Crovetto F, Del Mar Gil M, Delgado-López C, Divakar H, Driscoll AJ, Favre G, Fernandez Buhigas I, Flaherman V, Gale C, Godwin CL, Gottlieb S, Gratacós E, He S, Hernandez O, Jones S, Joshi S, Kalafat E, Khagayi S, Knight M, Kotloff KL, Lanzone A, Laurita Longo V, Le Doare K, Lees C, Litman E, Lokken EM, Madhi SA, Magee LA, Martinez-Portilla RJ, Metz TD, Miller ES, Money D, Moungmaithong S, Mullins E, Nachega JB, Nunes MC, Onyango D, Panchaud A, Poon LC, Raiten D, Regan L, Sahota D, Sakowicz A, Sanin-Blair J, Stephansson O, Temmerman M, Thorson A, Thwin SS, Tippett Barr BA, Tolosa JE, Tug N, Valencia-Prado M, Visentin S, von 225. Dadelszen P, Whitehead C, Wood M, Yang H, Zavala R, Tielsch JM. Clinical risk factors of adverse outcomes among women with COVID-19 in the pregnancy and postpartum period: a sequential, prospective meta-analysis. Am J Obstet Gynecol. 2023 Feb;228(2):161-177

  135. Peer N, Nguyen KA, Hill J, Sumner AE, Cikomola JC, Nachega JB, Kengne AP. Prevalence and influences of diabetes and prediabetes among adults living with HIV in Africa: a systematic review and meta-analysis. J Int AIDS Soc. 2023 Mar;26(3):e26059

  136. ?Nakimuli-Mpungu E, Wamala K, Nalugya JS, Nakanyike C, Iya J, Bakeera Kitaka S, Diana Namuli J, Akimana B, Nachega JB, Mills EJ, Seggane M. The effect of group support psychotherapy on adherence to anti-retroviral therapy and viral suppression among HIV positiveyoung people: Study protocol for a pilot randomized controlled trial. Front Health Serv. 2023 Apr 5; 3:1011898.

  137. Nachega JB, Scarsi KK, Gandhi M, Scott RK, Mofenson LM, Archary M, Nachman S, Decloedt E, Geng EH, Wilson L, Rawat A, Mellors JW. Long-acting antiretrovirals and HIV treatment adherence. Lancet HIV. 2023 May;10(5):e332-e342

  138. Petersen E, Hui DS, Nachega JB, Ntoumi F, Goletti D, Aklillu E, Sharma A, Nyirenda T, Yeboah-Manu D, Satta G, da Costa C, Azhar EI, Bockarie M, Al-Abri S, McHugh TD, Rodriguez-Morales AJ, Varghese GM, Zumla A. End of the Bedaquiline patent - a crucial development for moving forward affordable drugs, diagnostics, and vaccines for infectious diseases in low- and middle-income countries. Int J Infect Dis. 2023 Jun;131:180-182

  139. Gandhi M, Nachega J, Miller V, Wilkin T. Benefits, and limitations of different study designs for long-acting antiretroviral therapy among people living with HIV with viremia. J Int AIDS Soc. 2023 Jul;26 Suppl 2(Suppl 2):e26093.

  140. Nachega JB, Mbala-Kingebeni P, Rosenthal PJ, Rimoin AW, Hoff NA, Liesenborghs L, Vanlerberghe V, Andrei G, Rawat A, Wilson LA, Forrest J, Mills EJ, Hermans MP, Mulangu S, Ntoumi F, Zumla A, Muyembe-Tamfum JJ. The Human Mpox Global Outbreak: Available Control Tools and the Opportunity to Break a Cycle of Neglect in Endemic Countries. Am J Trop Med Hyg. 2023 Aug 14;109(4):719-724.

  141. Nakimuli-Mpungu E, Wamala K, Nalugya JS, Nakanyike C, Iya J, Bakeera Kitaka S, Diana Namuli J, Akimana B, Nachega JB, Mills EJ, Seggane M. The effect of group support psychotherapy on adherence to anti-retroviral therapy and viral suppression among HIV positive young people: Study protocol for a pilot randomized controlled trial. Front Health Serv. 2023 Apr 5;3:1011898.

  142. Byamungu LN, Nachega JB, Pillay A, Katoto PDMC, Jeena P, Zurba L, Masekela R. Predictors associated with critical care need and in-hospital mortality among children with laboratory-confirmed COVID-19 infection in a high HIV infection burden region. Front Pediatr. 2023 Sep 7;11:1252886. doi: 10.3389/fped.2023.1252886. eCollection 2023

  143. Kilmarx PH, Maitin T, Adam T, Aslanyan G, Cheetham M, Cruz J, Eigbike M, Gaye O, Jones CM, Kupfer L, Lindo J, Mijumbi R, Nachega JB, Nishi JB, Pantelidou I, Sarker M, Swaminathan S. Increasing Effectiveness and Equity in Strengthening Health Research Capacity Using Data and Metrics: Recent Advances of the ESSENCE Mechanism. Ann Glob Health. 2023 Jun 2;89(1):38. doi: 10.5334/aogh.3948. eCollection 2023

  144. Bidashimwa D, Ditekemena JD, Sigwadhi LN, Nkuta LM, Engetele E, Kilundu A, Chabikuli ON, Nachega JB. Completion of isoniazid preventive therapy for latent tuberculosis infection among children and adolescents compared to adults living with HIV in Kinshasa, Democratic Republic of the Congo. Trop Med Int Health. 2024 Feb;29(2):88-95.

  145. Chabikuli ON, Ditekemena JD, Sigwadhi LN, Mulenga A, Mboyo A, Bidashimwa D, Nachega JB. Advanced HIV Disease at Antiretroviral Therapy Initiation and Treatment Outcomes Among Children and Adolescents Compared to Adults Living With HIV in Kinshasa, Democratic Republic of the Congo. J Int Assoc Provid AIDS Care. 2023 Jan-Dec;22:23259582231221955.

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