????????????????Division of Med??ical Microbio??logy?

Publications??


2022

Journal articles

  1. ENGELBRECHT A, VAN RENSBURG R, DA COSTA D, CHOTHIA M. Aspergillus fumigatus: a rare cause of peritonitis in a peritoneal dialysis patient (a case report). Pan African Medical Journal 2022; 43(35):10.11604, 7 pages. https://doi.org/10.11604/pamj.2022.43.35.32583??

  2. DOWLING WB, WHITELAW AC, NEL P. Tracing TB: Are there predictors for active TB disease in patients with Xpert Ultra trace results?. International Journal of Infectious Diseases 2022; 114:115-123. https://doi.org/10.1016/j.ijid.2021.10.056??

  3. CORNELISSEN HM, MUSEKWA EM, GLASHOFF RH, ESSER MM, DZIKITI M, ABRAHAM DR, CHAPANDUKA ZC. Peripheral-blood cytopenia, an early indicator of inborn errors of immunity. British Journal of Haematology 2022; 198:875-886. https://doi.org/10.1111/bjh.18337?

  4. RUHANYA V, JACOBS GB, PAUL RH, JOSKA J, SEEDAT 5, NYANDORO G, GLASHOFF RH, ENGELBRECHT S. HIV-1 subtype C Tat exon-1 amino acid residue 24K is a signature for neurocognitive impairment. Journal of Neurovirology 2022; 28(3):392-403. https://doi.org/10.1007/s13365-022-01073-4?

  5. RUHANYA V, JACO?BS GB, PAUL RH, JOSKA JA, SEEDAT S, NYANDORO G, GLASHOFF RH, ENGELBRECHT S. HIV-1 subtype C Vpr amino acid residue 45Y and specific conserved fragments are associated with neurocognitive impairment and markers of viral load. AIDS Research and Human Retroviruses; ?http://doi.org/10.1089/AID.2022.0022. https://doi.org/10.1089/AID.2022.0022?

  6. NEL VAN ZYL K, MATUKANE SR, HAMMAN BL, WHITELAW AC, NEWTON-FOOT M. Effect of antibiotics on the human microbiome: a systematic review. International Journal of Antimicrobial Agents 2022; 59(2):1-32. https://doi.org/10.1016/j.ijantimicag.2021.106502

  7. MOSIME LB, NEWTON-FOOT M, NEL P. Fosfomycin resistan?ce in community-acquired urinary pathogens from Western Cape, SA. Southern African Journal of Infectious Diseases (Formerly Southern African Journal of Epidemiology and Infection) 2022; 37(1):1-4. https://doi.org/10.4102/sajid.v37i1.321? 

  8. ?GOUSSARD P, EBER E, MFINGWANA L, NEL P, SCHUBERT P, JANSON JT, PITCHER RD, NAUDE CE. Paediatric pulmonary echinococcosis: A neglected disease. Paediatric Respiratory Reviews 2022; 43 11-23. https://doi.org/10.1016/j.prrv.2021.11.001

  9. GOUSSARD P, EBER E, RABIE H, NEL P, SCHUBERT P. Paediatric pulmonary actinomycosis: A forgotten disease. Paediatric Respiratory Reviews 2022; 1(1):1. https://doi.org/10.1016/j.prrv.2021.09.001?

  10. SINGH S, NEWTON-FOOT M, NEL P, PIENAAR C. Comparison of commercial assays and two-step approach to detect Clostridioides difficile in SA. African Journal of Laboratory Medicine 2022; 11(1):1-6. https://doi.org/10.4102/ajlm.v11i1.1809?

  11. OCLOO R, NYASINGA J, MUNSHI Z, HAMDY A, MARCINIAK T, SOUNDARARAJAN M, NEWTON-FOOT M, ZIEBUHR W, SHITTU A, REVATHI G, ABOUELFETOUH A, WHITELAW AC. Epidemiology and antimicrobial resistance of staphylococci other than Staphylococcus aureus from domestic animals and livestock in Africa: a systematic review. Frontiers in Veterinary Science 2022; 10:1-17.  https://doi.org/10.3389/fvets.2022.1059054?

  12. VAN ZYL KN, WHITELAW AC, HESSELING AC, SEDDON JA, DEMERS A, NEWTON-FOOT M. Fungal diversity in the gut microbiome of young South African children. BMC MICROBIOLOGY 2022; 22:201.?? https://doi.org/10.1186/s12866-022-02615-w?

  13. PECORARO AJK, HERBST PG, JANSON JT, WAGENAAR R, ISMAIL Z, TALJAARD JJ, PROZESKY HW, PIENAAR C, DOUBELL AF. Early surgery determines prognosis in patients with infective endocarditis: outcome in patients managed by an Endocarditis Team - a prospective cohort study. Cardiovascular Diagnosis and Therapy 2022; 12(4):453-463. https://doi.org/10.21037/cdt-21-590?

  14. PECORARO AJK, HERBST PG, JOUBERT LH, HASSAN KM, PIENAAR C, TALJAARD JJ, PROZESKY HW, JANSON JT, DOUBELL AF. Echocardiographic features of infective endocarditis in South Africa: A prospective cohort study. SAM) South African Medical Journal 2022; 112(5):321-327. http://dx.doi.org/10.7196/SAMJ.2022.v112i5.15910??

  15. PECORARO AJK, HERBST PG, PIENAAR C, TALJAARD JJ, PROZESKY HW, JANSON JT, DOUBELL AF. Modified Duke/European Society of Cardiology 2015 clinical criteria for infective endocarditis: time for an update?. Open Heart 2022; 9:e001856, 7 pages.  http://dx.doi.org/10.1136/openhrt-2021-001856

  16. ??DRAMOWSKI A, AIKEN AM, REHMAN AM, SNYMAN Y, REUTER S, GRUNDMANN H, SCOTT JAG, DE KRAKER MEA, WHITELAW AC. Mortality associated with third-generation cephalosporin resistance in Enterobacteriaceae bloodstream infections at one South African hospital. Journal of Global Antimicrobial Resistance 2022; 29:176-184. https://doi.org/10.1016/j.jgar.2022.03.001?

  17. ?ENGELBRECHT A, VAN DER WESTHUIZEN C, TALJAARD JJ. Ra??tionalising empirical antibiotics for bloodstream infections: A retrospective study at a South African district-level hospital. SAM] South African Medical Journal 2022; 112(1):27-33.  http://dx.doi.org/10.7196/SAMJ.2022.v112i1.15959???

  18. CARVALHO M, SANDS K, THOMSON K, PORTAL E, MATHIAS J, MILTON R, GILLESPIE D, DYER C, AKPULU C, BOOSTROM I, HOGAN P, SAIF H, FERREIRA A, NIETO M, HENDER T, HOOD K, ANDREWS R, WATKINS J, HASSAN B, CHAN GJ, BEKELE D, SOLOMON S, METAFARIA G, BASU S, NAHA S, WHITELAW AC et al. Antibiotic resistance genes in the gut microbiota of mothers and linked neonates with or without sepsis from low-and middle-income countries. Nature Microbiology 2022; 7:1337-1347.?                         https://doi.org/10.1038/s41564-022-01184-y???

  19. HATHORN FK, DE KOCK IH,? WASSERMAN E. Decision support for clinical laboratory test requisition: the utility of ICD-10 coding. South African Journal of Industrial Engineering 2022; 33(1):16-24. https://doi.org/10.7166/33-1-2556?

  20. DRAMOWSKI A, AUCAMP M, BEALES E, BEKKER A, COTTON MF, FITZGERALD FC, LABI A-K, RUSSELL N, STRYSKO J, WHITELAW AC, COFFIN S. Healthcare-Associated infection prevention interventions for neonates in resource-limited settings. Frontiers in Pediatrics 2022; 10:Article 919403. https://doi.org/10.3389/fped.2022.919403?

  21. ?HUSSAIN M, WHITELAW AC, PARKER A. A five-year retrospective descriptive study on the clinical characteristics and outcomes of candidaemia at a tertiary hospital in South Africa. IJID Regions 2022; 3:79-83. https://doi.org/10.1016/j.ijregi.2022.03.003?

  22. MILTON R, GILLESPIE D, DYER C, TAIYARI K, CARVALHO MJ, THOMSON K, SANDS K, PORTAL E, HOOD K, FERREIRA A, HENDER T, KIRBY N, MATHIAS 3, NIETO M, WATKINS J, BEKELE D, ABAYNEH M, SOLOMON S, BASU S, NANDY RK, SAHA B, IREGBU K, UWAEZUOLE 5, ZAHRA R, SHIRAZI H, WHITELAW AC et al. Neonatal sepsis and mortality in low-income and middle-income countries from a facility-based birth cohort: an international multisite prospective observational study. Lancet Global Health 2022; 10:661-672.            https://doi.org/10.1016/S2214-109X(22)00043-2?

  23. NYAWO GR, NAIDOO CC, WU BG, SULAIMAN I, CLEMENTE JC, LI Y, MINNIES S, REEVE BWP, MOODLEY S, RAUTENBACH C, WRIGHT CA, SINGH S, WHITELAW AC, SCHUBERT P, WARREN RM, SEGEL L, THERON GDV. More than Mycobacterium tuberculosis: site-of-disease microbial communities, and their functional and clinical profiles in tuberculous lymphadenitis. BMJ Open 2022; 0:1-12. https://doi.org/10.1136/thorax-2022-219103?

  24. PAPAVARNAVAS N, BRINK A, DLAMINI S, WASSERMAN S, WHITELAW AC, NTUSI NAB, MENDELSON M. Practice update to optimise the performance and interpretation of blood cultures: 2022. SAMJ South African Medical Journal 2022; 112(6):397-402.    https://doi.org/10.7196/SAMJ.2022.v112i6.16537?

  25. SANDS K, CARVALHO MJ, SPILLER 0 B, PORTAL E, THOMSEN KR, WATKINS J, MATHIAS 3, DYER C, AKPULU C, ANDREWS R, FERREIRA A, HENDER T, MILTON R, NIETO M, ZAHRA R, SHIRAZI H, MUHAMMAD A, AKIF 5, JAN M H, IREGBU K, MODIBBO F, UWAEZUOKE 5, CHAN GJ, BEKELE D, WHITELAW AC et al. Characterisation of Staphylococci species from neonatal blood cultures in low- and middle-income countries. BMC Infectious Diseases 2022; 22:1-16. https://doi.org/10.1186/s12879-022-07541-w??

  26. SOWDEN M, VAN NIEKERK E, BULABULA ANH, DRAMOWSKI A, WHITELAW AC, TWISK J, VAN WEISSENBRUCH MM. Impact of a multi-strain probiotic administration on peri-rectal colonization with drug-resistant Gram-negative bacteria in preterm neonates. Frontiers in Pediatrics 2022; 10(1002762):10 pages.? https://doi.org/10.3389/fped.2022.1002762?


2021

Journal articles

  1. ALSEQELY M, NEWTON-FOOT M, KHALIL A, EL NAKEEB M, ABOUELFETOUH A, WHITELAW AC. Association between fluoroquinolone resistance and MRSA genotype in Alexandria, Egypt. Scientific Reports 2021; 11(4253):1-9. https://doi.org/10.1038/s41598-021-83578-2?

  2. AMENYOGBE N, DIMITRU P, SMOLEN KK, BROWN EM, SHANNON CP, TEBBUTT SJ, COOPER PJ, MARCHANT A, GOETGHEBUER T, ESSER MM, FINLAY BB, KOLLMANN TR, MOHN WW. Biogeography of the Relationship between the Child Gut Microbiome and the Innate Immune System. ASM Science Journal 2021; 12(1):1-18. https://dx.doi.org/10.1128%2FmBio.03079-20

  3. CORNELISSEN HM, GLANZMANN B, VAN COLLER A, ENGELBRECHT C, ABRAHAM DR, REDDY K, MOLLER M, KINNEAR CJ, GLASHOFF RH, ESSER MM. Mendelian susceptibility to mycobacterial disease in tuberculosis-hyperendemic South Africa. SAMJ South African Medical Journal 2021; 111(10):998-1005. http://dx.doi.org/10.7196%2FSAMJ.2021.v111i10.15341?

  4. DA COSTA D, NEL P. Re-decontamination of liquid mycobacterial cultures: Additional Mycobacterium tuberculosis yield in the era of Xpert MTB/RIF Ultra in Cape Town, South Africa. African Journal of Laboratory Medicine  2021; 10(1):1-3. https://doi.org/10.4102/ajlm.v10i1.1529?

  5. DOWLING WB, VAN DER WESTHUYZEN M, HAUMANN M, REDDY K. Non-toxigenic vibrio cholerae non-O1/non-O139 pseudobacteraemia in a neonate: A case report. Southern African Journal of Infectious Diseases (Formerly Southern African Journal of Epidemiology and Infection) 2021; 36(1):1-4.? https://doi.org/10.4102/sajid.v36i1.263? 

  6. DRAMOWSKI A, AUCAMP M, BEKKER A, PILLAY S, MOLOTO K, WHITELAW AC, COTTON MF, COFFIN S. NeoCLEAN: a multimodal strategy to enhance environmental cleaning in a resource-limited neonatal unit. Antimicrobial Resistance and Infection Control 2021; 10:35. https://doi.org/10.1186/s13756-021-00905-y?

  7. DRAMOWSKI A, BEKKER A, COTTON MF, WHITELAW AC, COFFIN S. Epidemiology of clinically suspected and laboratory-confirmed bloodstream infections at a South African neonatal unit. Journal of Infection in Developing Countries 2021; 15(7):943-952. https://doi.org/10.3855/jidc.13971?

  8. DRAMOWSKI A, ONG'AYO G, REHMAN AM, WHITELAW AC, LABI A-K, OBENG-NKRUMAH N, NDIR A, MAGWENZI MT, WOLKEWITZ M, DE KRAKER MEA, SCOTT JAG, ET AL AL. Mortality attributable to third-generation cephalosporin resistance in Gram-negative bloodstream infections in African hospitals: a multi-site retrospective study. JAC-Antimicrobial Resistance 2021; 3(1):dlaa130. http://dx.doi.org/10.1093/jacamr/dlaa130?

  9. DRAMOWSKI A, PILLAY S, BEKKER A, ABRAHAMS I, COTTON MF, COFFIN S, WHITELAW AC. Impact of 1% chlorhexidine gluconate bathing and emollient application on bacterial pathogen colonization dynamics in hospitalized preterm neonates – A pilot clinical trial. EClinicalMedicine 2021; 37:100946. https://doi.org/10.1016/j.eclinm.2021.100946?

  10. ENGELBRECHT C, URBAN MF, SCHOEMAN M, PAARWATER BA, VAN COLLER A, ABRAHAM DR, CORNELISSEN HM, GLASHOFF RH, ESSER MM, MOLLER M, KINNEAR CJ, GLANZMANN B. Clinical utility of whole exome sequencing and targeted panels for the identification of inborn errors of immunity in a resource-constrained setting. Frontiers in Immunology 2021; 12:1-12.  https://doi.org/10.3389/fimmu.2021.665621

  11. FERREIRA N, REDDY K, VENTER RG, LAUBSCHER M. Antibiogram profiles and efficacy of antibiotic regimens of bacterial isolates from chronic osteomyelitis of the appendicular skeleton: A developing-world perspective. SAMJ South African Medical Journal 2021; 111(7):642648. https://doi.org/10.7196/samj.2021.v111i7.15516?

  12. GLANZMANN B, JOOSTE TL, GHOOR S, GORDON R, MIA R, LI H, MAO J, CHARLS P, DOUMAN C, KOTZE MJ, PEETERS AV, LOOTS G, ESSER MM, TIEMESSEN CT, WILKINSON RJ, LOUW J, GRAY G, MOLLER M, WARREN RM, KINNEAR CJ. Human whole genome sequencingin South Africa . Scientific Reports 2021; 11:606, 8 pages. https://doi.org/10.1038/s41598-020-79794-x?

  13. GOUSSARD P, CROUCAMP R, BOSCH C, DEMERS A, MORRISON J, MFINGWANA L, PALMER M, VAN DER ZALM MM, FRIEDRICH SO, JANSON JT, WHITELAW AC, ANDRONIKOU S, HESSELING AC, WALTERS E, LOPEZ VARELA EB. Diagnostic utility of bronchoalveolar lavage in children with complicated intrathoracic tuberculosis. Pediatric Pulmonology 2021; 56(7):2186-2194. https://doi.org/10.1002/ppul.25405??

  14. GOUSSARD P, RABIE H, MARSHALL M, MFINGWANA L, MORRISON J, ISMAIL MZ, RETIEF FW, NEL P, DA COSTA D, ANDRONIKOU S, SCHUBERT P. Endobronchial actinomycosis in a child. Pediatric Pulmonology 2021; 56(10):3429-3432. https://doi.org/10.1002/ppul.25550

  15. KUMAR S, BOUIC PJD, ROSENKRANZ BF. Investigation of CYP2B6, 3A4 and β-esterase interactions of Withania somnifera (L.) dunal in human liver microsomes and HepG2 cells. Journal of Ethnopharmacology 2021; 24(270):113766, 16 pages. https://doi.org/10.1016/j.jep.2020.113766?

  16. MASHIGO N, ESSER MM. Game of Clones: A case of ELANE gene mutation-related neutropenia . Journal of Medical Laboratory Science and Technology ( Formelry Medical Technology SA) 2021; 3(1):8-10. http://dx.doi.org/10.36303/JMLSTSA.2021.3.1.65?

  17. MINNIES S, REEVE BWP, ROCKMAN LT, NYAWO GR, NAIDOO CC, KITCHIN N, RAUTENBACH C, WRIGHT CA, WHITELAW AC, SCHUBERT P, WARREN RM, THERON GDV. Xpert MTB/RIF Ultra is highly sensitive for the diagnosis of tuberculosis lymphadenitis in an HIV-endemic setting . Journal of Clinical Microbiology 2021; 59(12):e01316-21, 11 pages. https://doi.org/10.1128/jcm.01316-21?

  18. MOOLLA MS, REDDY K, FWEMBA I, NYASULU PRS, TALJAARD JJ, PARKER A, LOUW EH, NORTJE AJ, PARKER MA, LALLA U, KOEGELENBERG CFN, ALLWOOD BW. Bacterial infection, antibiotic use and COVID-19: Lessons from the intensive care unit. SAMJ South African Medical Journal 2021; 111(6):575-581. https://doi.org/10.7196/SAMJ.2021.v111i6.15590?

  19. MOOLLA MS, WHITELAW AC, DECLOEDT EH, KOEGELENBERG CFN, PARKER A. Opportunities to enhance antibiotic stewardship: colistin use and outcomes in a low-resource setting. JAC-Antimicrobial Resistance 2021; 3(4):doi.org/10.1093/jacamr/dlab169, 7 pages. https://dx.doi.org/10.1093%2Fjacamr%2Fdlab169?

  20. NEL VAN ZYL K, WHITELAW AC, HESSELING AC, SEDDON JA, DEMERS A, NEWTON-FOOT M. Association between clinical and environmental factors and the gut microbiota profiles in young South African children. Scientific Reports 2021; 11:15895. https://dx.doi.org/10.1038/s41598-021-95409-5?

  21. PECORARO AJK, HERBST PG, PIENAAR C, TALJAARD JJ, PROZESKY HW, JANSON JT, DOUBELL AF. Bartonella species as a cause of culture-negative endocarditis in South Africa. European Journal of Clinical Microbiology and Infectious Diseases 2021; 40:1873-1879. https://doi.org/10.1007/s10096-021-04239-w?

  22. PECORARO AJK, PIENAAR C, HERBST PG, POERSTAMPER S, JOUBERT LH, TALJAARD JJ, PROZESKY HW, JANSON JT, NEWTON-FOOT M, DOUBELL AF. Causes of infective endocarditis in the Western Cape, South Africa: a prospective cohort study using a set protocol for organism detection and central decision making by an endocarditis team. BMJ Case Reports 2021; 11:e053169, 8 pages. https://doi.org/10.1136/bmjopen-2021-053169?

  23. REDDY K, BEKKER A, WHITELAW AC, ESTERHUIZEN T, DRAMOWSKI A. A retrospective analysis of pathogen profile, antimicrobial resistance and mortality in neonatal hospital-acquired bloodstream infections from 2009-2018 at Tygerberg Hospital, South Africa. PLoS One 2021; 16(1):e0245089. https://doi.org/10.1371/journal.pone.0245089?

  24. REDDY K, GERICKE SH, RABIE H, PIENAAR C, MALOBA MRB. Exudative pharyngitis and Corynebacterium pseudodiphtheriticum: A case report and review of the literature. Southern African Journal of Infectious Diseases (Formerly Southern African Journal of Epidemiology and Infection) 2021; 36(1):a225. https://doi.org/10.4102/sajid.v36i1.225?

  25. REDDY K, WHITELAW AC. Can the Xpert MRSA/SA BC assay be used as an antimicrobial stewardship tool? A prospective assay validation and descriptive impact assessment study in a South African setting. BMC Infectious Diseases 2021; 21(177):1-9. https://doi.org/10.1186/s12879-021-05857-7?

  26. RUHANYA V, JACOBS GB, NAIDOO S, PAUL RH, JOSKA JA, SEEDAT S, NYANDORO G, ENGELBRECHT S, GLASHOFF RH. Impact of Plasma IP-10/CXCL10 and RANTES/CCL5 Levels on Neurocognitive Function in HIV Treatment-Na?ve Patients . AIDS Research and Human Retroviruses 2021; 37(9):657-665. https://doi.org/10.1089/aid.2020.0203?

  27. RUHANYA V, JACOBS GB, PAUL RH, JOSKA JA, SEEDAT S, NYANDORO G, ENGELBRECHT S, GLASHOFF RH. Plasma cytokine biomarker cutoff values for HIV-associated neurocognitive impairment in adults. VIRAL IMMUNOLOGY 2021; 34(10):1-8. https://doi.org/10.1089/vim.2021.0047?

  28. RUHANYA V, JACOBS GB, PAUL RH, JOSKA JA, SEEDAT S, NYANDORO G, ENGELBRECHT S, GLASHOFF RH. Plasma cytokine levels as predictors of global and domain-specific human immunodeficiency virus-associated neurocognitive impairment in treatment-naive individuals . JOURNAL OF INTERFERON AND CYTOKINE RESEARCH 2021; 41(4):153-160. https://doi.org/10.1089/jir.2020.0251?

  29. SANDS K, CARVALHO J, PORTAL E, THOMSON K, DYER C, AKPULU C, ANDREWS R, FERREIRA A, GILLESPIE D, HENDER   T, HOOD K, MATHIAS J, MILTON R, NIETO M, TAIYARI K, CHAN GJ, BEKELE D, SOLOMON S, BASU S, CHATTOPADHYAY P, MUKHERJEE S, IREGBU K, MODIBBO F, UWAEZUOKE S. Characterisation of antimicrobial-resistant Gram-negative bacteria that cause neonatal sepsis in seven low-and middle-income countries. Nature Microbiology 2021; 6:512-523. https://doi.org/10.1038/s41564-021-00870-7?

  30. SHUPING L, MPEMBE RS, MHLANGA M, NAICKER S, TSOTETSI E, WADULA J, VELAPHI S, NAKWA F, CHIBABHAI V, MAHABEER P, MONCHO M, PRENTICE E, BAMFORD CM, REDDY K, MALULEKA C, MAWELA D, MODISE M, GOVENDER NP. Epidemiology of culture-confirmed candidemia among hospitalised children in South Africa, 2012 - 2017. Pediatric Infectious Disease Journal 2021; 20(20):18. https://doi.org/10.1097/inf.0000000000003151?

  31. SNYMAN Y, REUTER S, WHITELAW AC, STEIN L, MALOBA MRB, NEWTON-FOOT M. Characterisation of mcr-4.3 in a colistin-resistant Acinetobacternosomialis clinical isolate from Cape Town, South Africa. Journal of Global Antimicrobial Resistance 2021; 25:102-106. https://doi.org/10.1016/j.jgar.2021.03.002?

  32. SNYMAN Y, WHITELAW AC, BARNES JM, MALOBA MRB, NEWTON-FOOT M. Characterisation of mobile colistin resistance genes (mcr-3 and mcr-5) in river and storm water in regions of the Western Cape of South Africa. Antimicrobial Resistance and Infection Control 2021; 10(96):1-9. https://doi.org/10.1186/s13756-021-00963-2?

  33. SNYMAN Y, WHITELAW AC, MALOBA MRB, HESSELING AC, NEWTON-FOOT M. Carriage of colistin-resistant Gram-negative bacteria in children from communities in Cape Town (Tuberculosis child multidrug-resistant preventive therapy trial sub-study). Southern African Journal of Infectious Diseases (Formerly Southern African Journal of Epidemiology and Infection) 2021; 36(1):a241. https://doi.org/10.4102/sajid.v36i1.241?

  34. SNYMAN Y, WHITELAW AC, REUTER S, MALOBA MRB, NEWTON-FOOT M. Colistin resistance mechanisms in clinical Escherichia coli and Klebsiella spp. Isolates from the Western Cape of South Africa. Microbial Drug Resistance 2021; 27(9):1249-1258. https://doi.org/10.1089/mdr.2020.0479?

  35. TEER E, JOSEPH DE, DOMINICK LL, GLASHOFF RH, ESSOP MF. Expansion of GARP-Expressing CD4 CD25 FoxP3 T Cells and SATB1 Association with activation and coagulation in immune compromised HIV-1-infected individuals in South Africa. VIROLOGICA SINICA 2021; 36:1133-1143. https://doi.org/10.1007/s12250-021-00386-8?

  36. TEER E, JOSEPH DE, GLASHOFF RH, ESSOP MF. Monocyte/Macrophage-Mediated Innate Immunity in HIV-1 infection: from early response to late dysregulation and links to cardiovascular diseases onset. VIROLOGICA SINICA 2021; 36:565-576. https://dx.doi.org/10.1007%2Fs12250-020-00332-0?

  37. THOMSON K, DYER C, LIU F, SANDS K, PORTAL E, CARVALHO MJ, BARRELL M, BOOSTROM I, DUNACHIE S, FARZANA R, FERREIRA A, FRAYNE F, HASSAN B, JONES E, JONES L, MATHIAS J, MILTON R, REES J, CHAN GJ, BEKELE D, MAHLET A, SAHA B, IREGBU K, MODIBBO F, UWAEZUOKE S, Z. Effects of antibiotic resistance, drug target attainment, bacterial pathogenicity and virulence, and antibiotics access and affordability on outcomes in neonatal sepsis: an internal microbiology and drug evaluation prospective substudy (BARNARDS). The Lancet Digital Health 2021; 21(12):1677-1688. https://doi.org/10.1016/s1473-3099(21)00050-5? ?

  38. VAN COLLER A, GLANZMANN B, CORNELISSEN HM, MOLLER M, KINNEAR CJ, ESSER MM, GLASHOFF RH. Phenotypic and immune functional profiling of patients with suspected mendelian susceptibility to mycobacterial disease in South Africa. BMC IMMUNOLOGY 2021; 22:62. https://doi.org/10.1186/s12865-021-00452-6?

  39. VAN DER MERWE LW, DA COSTA D, REDDY K, MEYER D. Delayed-onset post-operative keratitis and endophthalmitis caused by Exophiala oligosperma. Journal of Ophthalmic Inflammation and Infection 2021; 11(46):1-5. https://doi.org/10.1186/s12348-021-00277-9?? ??

?

2020

Journal articles?

  1. ABDULGADER SMAA, VAN RIJSWIJK A, WHIT?ELAW AC, NEWTON-FOOT M. The association between pathogen factors and clinical outcomes in patients with Staphylococcus aureus bacteraemia in a tertiary hospital, Cape Town. International Journal of Infectious Diseases 2020; 91:111-118. http://doi.org/10.1016/j.ijid?.2019.11.032???

  2. ABDULGADER SMAA, WHITELAW AC, LENTSWE TI, NEWTON-FOOT M. The prevalence and molecular mechanisms of mupirocin resistance in Staphylococcus aureus isolates from a Hospital in Cape Town, South Africa. Antimicrobial Resistance and Infection Control 2020; 9(47):47, 7 pages. https://doi.org/10.1186/s13756-020-00707-8??

  3. AMENYOGBE N, DIMITRIU P, CHO P, RUCK CE, FORTUNO ES, CAI B, ALIMENTI A, C?TE HCF, MAAN EJ, SLOGROVE AL, ESSER MM, MARCHANT A, ET AL ET. Innate Immune Responses and gut microbiomes distinguish HIV-Exposed from HIV Unexposed children in a population-specific manner. JOURNAL OF IMMUNOLOGY 2020; 205:2618-2628. https://doi.org/10.4049/jimmunol.2000040??

  4. AMIRALI MH, LIEBENBERG JJ, PILLAY S, NEL JD. Sporotrichosis in renal transplant patients: two case reports and a review of the literature. Journal of Medical Case Reports 2020; 14:79, 9 pages. https://doi.org/10.1186/s13256-020-02385-x?

  5. DOWLING WB, KOEN JG. Corynebacterium jeikeium native valve infective endocarditis. European Heart Journal - Case Reports 2020; 4:1-4. https://doi.org/10.1093/ehjcr/ytaa365??

  6. DOWLING WB, OPPERMAN C. Is there value in a two-step diagnostic algorithm to confirm SARS-CoV-2 in South Africa?. SAMJ South African Medical Journal 2020; 10(7):564-565. https://doi.org/10.7196/SAMJ.2020.v110i7.14853?

  7. GLANZMANN B, MOLLER M, SCHOEMAN M, URBAN MF, VAN HELDEN PD, FRIGATI LJ, GREWAL R, PIETERS H, LOOS B, VAN HELDEN EG, GLASHOFF RH, CORNELISSEN HM, RABIE H, ESSER MM, KINNEAR CJ. Identification of a novel WAS mutation in a South African patient presenting with atypical Wiskott-Aldrich syndrome: a case report. BMC Medical Genetics 2020.  https://doi.org/10.1186/s12881-020-01054-6?

  8. KUMAR S, BOUIC PJD, ROSENKRANZ BF. In Vitro Assessment of the Interaction Potential of Ocimum basilicum (L.) Extracts on CYP2B6, 3A4, and Rifampicin Metabolism. Frontiers in Pharmacology 2020; 11(5):517. https://dx.doi.org/10.3389%2Ffphar.2020.00517?

  9. LI G, BIELICKI JA, AHMED ASMNU, ISLAM MS, BEREZIN EM, GALLACCI CB, GUINSBURG R, FIGUEIREDO CED, VIEIRA RS, SILVA R, TEIXEIRA C, TURNER P, DRAMOWSKI A, BEKKER A, WHITELAW AC, ET AL ET. Towards understanding global patterns of antimicrobial use and resistance in neonatal sepsis: insights from the NeoAMR network. ARCHIVES OF DISEASE IN CHILDHOOD 2020; 105:26-31. https://doi.org/10.1136/archdischild-2019-316816??

  10. MAPONGA TG, GLASHOFF RH, VERMEULEN H, ROBERTSON B, BURMEISTER S, BERNON MM, OMOSHORO-JONES JA, RUFF P, NEUGUT AI, JACOBSON JS, PREISER W, ANDERSSON MI. Hepatitis B virus-associated hepatocellular carcinoma in SA in the era of HIV. BMC GASTROENTEROLOGY 2020; 20(226):1-10. https://doi.org/10.1186/s12876-020-01372-2?

  11. MAZAZA A, LALLA U, TALJAARD JJ, JOHN TJ, JOHN K, SLABBERT JT, KOEGELENBERG CFN. The aetiology of severe community-acquired pneumonia requiring intensive care unit admission in the Western Cape Province, South Africa. African Journal of Thoracic and Critical Care Medicine ( Previously South African Respiratory Journal). 2020; 26(1):5-7. http://dx.doi.org/10.7196/AJTCCM.2020.v26i1.035?

  12. NAICKER S, MPEMBE RS, MAPHANGA T, ZULU TG, DESANTO D, WADULA J, MVELASE N, MALULEKA C, REDDY K, DAWOOD H, MALOBA MRB, GOVENDER NP. Decreasing fluconazole susceptibility of clinical South African Cryptococcus neoformans isolates over a decade. PLoS Neglected Tropical Diseases 2020; 14(3):e0008137, 13 pages. https://doi.org/10.1371/journal.pntd.0008137?

  13. NEL VAN ZYL K, WHITELAW AC, NEWTON-FOOT M. The effect of storage conditions on microbial communities in stool. PLoS One 2020; 15(1):e0227486, 11 pages. https://doi.org/10.1371/journal.pone.0227486???

  14. PEROVIC O, ISMAIL H, QUAN V, BAMFORD CM, NANA T, CHIBABHAI V, BHOLA P, RAMJATHAN P, SWE SWE HAN K, WADULA J, WHITELAW AC, SMITH M, MBELLE N, SINGH-MOODLEY A. Carbapenem-resistant Enterobacteriaceae in patients with bacteraemia at tertiary hospitals in South Africa, 2015 to 2018. European Journal of Clinical Microbiology and Infectious Diseases 2020; 39:1287-1294.  https://doi.org/10.1007/s10096-020-03845-4

  15. RUHANYA V, JACOBS GB, NYANDORO G, PAUL RH, JOSKA JA, SEEDAT S, GLASHOFF RH, ENGELBRECHT S. Peripheral blood lymphocyte proviral DNA predicts neurocognitive impairment in clade C HIV. Journal of Neurovirology 2020; 26(6):920-928.  https://doi.org/10.1007/s13365-020-00882-9??

  16. SNYMAN Y, WHITELAW AC, REUTER S, DRAMOWSKI A, MALOBA MRB, NEWTON-FOOT M. Clonal expansion of colistin resistant Acinetobacter baumannii isolates in Cape Town, South Africa. International Journal of Infectious Diseases 2020; 91:94-100.  https://doi.org/10.1016/j.ijid.2019.11.021?

? 

?2019

Journal articles

  1. SPRINGER PE, SLOGROVE AL, KIDD M, KALK E, BETTINGER JA, ESSER MM, COTTON MF, ZUNZA M, MOLTENO CD, KRUGER M. Neurodevelopmental and behavioural outcomes of HIV-exposed uninfected and HIV-unexposed children at 2–3 years of age in Cape Town, South Africa. AIDS CARE-PSYCHOLOGICAL AND SOCIO-MEDICAL ASPECTS OF AIDS/HIV 2020; 32(4):411-419.  https://doi.org/10.1080/09540121.2019.1637506?

  2. VAN STRATEN A, BLOKLAND RA, LOOCK JW, WHITELAW AC. Potential Ototopical Antiseptics for the treatment of active chronic otitis media: an in vitro evaluation. Otology and Neurotology 2020; 41:e1060 - e1065.? https://doi.org/10.1097/MAO.0000000000002728?

  3. LAUGHTON B, NAIDOO S, DOBBELS EFM, BOIVIN M, JANSE VAN RENSBURG A, GLASHOFF RH, VAN ZYL GU, KRUGER M, COTTON MF. Neurodevelopment at 11 months after starting antiretroviral therapy within 3 weeks of life. Southern African Journal of HIV Medicine 2019; 20(1):a1008, 8 pages. https://doi.org/10.4102/sajhivmed.v20i1.1008

  4. MURPHY RJT, RAMSAY JP, LEE YT, PANG S, O'DEA MA, PEARSON JC, AXON JE, RABY E, ABDULGADER SMAA, WHITELAW AC, COOMBS GW. Multiple introductions of methicillin-resistant Staphylococcus aureus ST612 into Western Australia associated with both human and equine reservoirs. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS 2019; 54(6):681-685.  https://doi.org/10.1016/j.ijantimicag.2019.08.022??

  5. NEL P, PATERSON LA, HOFFMANN R. Carbapenemase-producing Enterobacteriaceae colonization in adult inpatients: A point prevalence study. Southern African Journal of Infectious Diseases 2019; 34(1):a129, 5 pages. https://doi.org/10.4102/sajid.v34i1.129?

  6. SHAFEE M, ABBAS F, TANVEER Z, WHITELAW AC, AH TOW L, ASHRAF M, AHMAD I, PATCHING SG, JABBAR A, AKBAR A, MUSTAFA M. Predominance of Central Asian strain (ST 26) in Mycobacterium tuberculosis isolates from Balochistan by spoligotyping. Journal of Infection in Developing Countries 2019; 13(7):619-625. https://doi.org/10.3855/jidc.10803?

  7. TEER E, JOSEPH DE, DRIESCHER N, NELL TA, DOMINICK LL, MIDGLEY NEK, DESHPANDE G, PAGE MJ, PRETORIUS E, WOUDBERG NJ, LECOUR S, GLASHOFF RH, ESSOP MF. HIV and cardiovascular diseases risk: exploring the interplay between T-cell activation, coagulation, monocyte subsets and lipid subclass alterations. American Journal of Physiology - Heart and Circulatory Physiology 2019; 316:1146-1157. https://doi.org/10.1152/ajpheart.00797.2018?

  8. WALTERS E, VAN DER ZALM MM, DEMERS A, WHITELAW DA, PALMER M, BOSCH C, DRAPER HR, SCHAAF HS, GOUSSARD P, LOMBARD CJ, GIE RP, HESSELING AC. Specimen Pooling as a Diagnostic Strategy for Microbiologic Confirmation in Children With Intrathoracic Tuberculosis. Pediatric Infectious Disease Journal 2019; 38(6):e128-e131. https://doi.org/10.1097/inf.0000000000002240??

Chapters in Books

  1. BOUIC PJD. Evaluation of buchu extracts in vitro: Evidence of its anti-glycaemic and anti-inflammatory properties. In: HUISAMEN B (ed.) Medicinal Effects of Agathosma (Buchu) Extracts, Aosis, Cape Town, South Africa, 2019: 17-28.  https://www.semanticscholar.org/paper/Evaluation-of-buchu-extracts-in-vitro%3A-Evidence-of-Bouic/619ea4af6964074c3b5a9dc6ebf9e858775c09f0?

 

2018

Journal articles

  1. ALLAM M, JOSEPH L, ISMAIL F, SAID H, ISMAIL N, ISMAIL A, MNYAMENI F, MTSHALI S, GOUSSARD P, PEKEUR JC, LOURENS A, OMAR SV. Whole-Genome Sequence of a Mycobacterium goodie Isolate from a Paediatric Patient in South Africa. Genome Announcements 2018; 6(3):e01478-17. https://doi.org/10.1128/genomea.01478-17?

  2. CRICHTON H, O'CONNELL N, RABIE H, WHITELAW AC, DRAMOWSKI A. Neonatal and paediatric bloodstream infections: Pathogens, antimicrobial resistance patterns and prescribing practice at Khayelitsha District Hospital, Cape Town, South Africa. South African Medical Journal 2018; 108(2):99-104. https://doi.org/10.7196/samj.2017.v108i2.12601?

  3. DRAMOWSKI A, LLOYD LG, BEKKER A, HOLGATE SL, AUCAMP MC, REDDY K, FINLAYSON H. Neonatal listeriosis during a countrywide epidemic in South Africa: A tertiary hospital's experience. South African Medical Journal 2018; 108(10):818-827.  http://dx.doi.org/10.7196%2FSAMJ.2018.v108i10.13207

  4. DZIKITI M, ESSER MM, SLOGROVE AL, BETTINGER JA, MACHEKANO R, COTTON MF. Early Breastfeeding Cessation Among HIV?Infected and HIV?Uninfected Women in Western Cape Province, South Africa. AIDS and Behavior 2018; 22:S114-S120.    https://doi.org/10.1007/s10461-018-2208-0?

  5. FLEPISI TB, BOUIC PJD, SISSOLAK G, ROSENKRANZ BF. B-cell and T-cell activation in South African HIV-1-positive non-Hodgkin's lymphoma patients. Southern African Journal of HIV Medicine 2018; 19(1):1-7. https://doi.org/10.4102/sajhivmed.v19i1.809?

  6. GLANZMANN B, ABRAHAM DR, MOLLER M, GLASHOFF RH, VAN COLLER A, UREN CP, DURRHEIM GA, URBAN MF, VAN HELDEN EG, ESSER MM, RICE GI, CROW YJ, KINNEAR CJ. Variable expression in SAMHD1-Associated familial Aicardi-Goutieres syndromes. Current Allergy and Clinical Immunology 2018; 31(4):194-198. https://hdl.handle.net/10520/EJC-15b20d9fb5?

  7. GLANZMANN B, MOLLER M, MONCADA-VELEZ M, PETER J, URBAN MF, VAN HELDEN PD, VAN HELDEN EG, DE VILLIERS N, GLASHOFF RH, NORTJE SH, BUSTAMANTE J, ABEL L, CASANOVA J, BOISSON-DUPUIS S, ESSER MM, KINNEAR CJ. Autosomal Dominant IFN-Yr1 Deficiency Presenting with both Atypical Mycobacteriosis and Tuberculosis in a BCG Vaccinated South African Patient. JOURNAL OF CLINICAL IMMUNOLOGY 2018; 38(4):460-463. https://doi.org/10.1007/s10875-018-0509-8??

  8. KOOPMANS LR, FINLAYSON H, WHITELAW AC, DECLOEDT EH, DRAMOWSKI A. Paediatric antimicrobial use at a South African hospital. International Journal of Infectious Diseases 2018; 74:16-23. https://doi.org/10.1016/j.ijid.2018.05.020?

  9. SELEPE MM, VAN WYK AC, HOEK KGP, VAN HELDEN PD, WARREN RM, WRIGHT CA. Papanicolaou induced fluorescence, Ziehl-Neelsen and Auramine O Strains on lymph node fine needle aspiration biopsy specimens from children: A Comparative study. DIAGNOSTIC CYTOPATHOLOGY 2018; 46(7):589-592. https://doi.org/10.1002/dc.23956??

  10. SINGH-MOODLEY A, DUSE A, NAICKER P, KULARATNE R, NANA T, LEKALAKALA R, MBELLE N, DAWOOD H, SWE SWE HAN K, RAMJATHAN P, BHOLA P, WHITELAW AC, PEROVIC O. Laboratory based antimicrobial resistance surveillance for Pseudomonas aeruginosa blood isolates from South Africa. Journal of Infection in Developing Countries 2018; 12(8):616-624.  https://doi.org/10.3855/jidc.9539

  11. GLANZMANN B, UREN C, DE VILLIERS N, VAN COLLER A, GLASHOFF RH, URBAN M, HOAL EG, ESSER MM, MOLLER M, KINNEAR CJ. Primary immunodeficiency diseases in a tuberculosis endemic region: challenges and opportunities. Genes and Immunity 20, 447–454 (2018).? https://doi.org/10.1038/s41435-018-0041-0?